KMID : 0366220080430040263
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Korean Journal of Hematology 2008 Volume.43 No. 4 p.263 ~ p.267
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Gullain-barre Syndrome Associated with Non-Hodgkin¡¯s Lymphoma
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Song Jun-Hwa
Park Keon-Uk Sim Young-Joo Jeon Jae-Yong Lee Seong-Jae Hyun Jae-Won Cho Yoon-Young Park Sung-Dong
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Abstract
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A 67-year-old man developed swelling of the right leg with inguinal and abdominal pain over a period of 5 days. Excisional biopsy of the left supraclavicular lymph nodes revealed the diffuse, large B cell type of malignant lymphoma. After chemotherapy, he complained of a tingling sensation and weakness in the left upper extremity, and then this progressed to quadriplegia. Electrodiagnostic testing demonstrated the characteristic findings of demyelination, which was consistent with Guillain-Barre syndrome (GBS). Non-Hodgkin¡¯s Lymphoma (NHL) leading to GBS, as was observed in the present case, suggests that physicians should be aware of GBS and non-Hodgkin¡¯s lymphoma as the full spectrum of these diseaseshas not been fully defined.
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KEYWORD
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Guillain-barre syndrome, Non-Hodgkin¡¯s lymphoma, Chemotherapy, Quadriplegia
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